What Is Nicotinamide?
Nicotinamide, also known as vitamin B3, is a water-soluble vitamin widely used in skincare for its multiple benefits. Topically, it enhances the skin barrier by increasing ceramide synthesis, helping the skin retain moisture and protecting against environmental stressors. Nicotinamide reduces inflammation, making it suitable for acne-prone or sensitive skin, and regulates sebum production to help manage oiliness and breakouts. It also improves skin tone and texture, reducing hyperpigmentation and fine lines, while supporting wound healing and overall skin resilience. These effects are well-documented in dermatological studies and highlight why nicotinamide is a key ingredient in many cosmetic formulations.
The Role of NAD+ in Skin Health
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme present in all living cells that plays a critical role in energy metabolism and DNA repair. In skin health, NAD+ is essential for the activity of enzymes like PARP-1, which repair damaged DNA and help maintain skin integrity. Restoring NAD+ levels reduces cellular senescence, promoting healthier and more youthful-looking skin. Additionally, NAD+ supports mitochondrial function, improving energy production in skin cells and contributing to overall skin vitality. Scientific research indicates that boosting NAD+ levels can have significant anti-aging effects.
Comparative Overview
Nicotinamide works primarily to enhance the skin barrier, reduce inflammation, and improve hydration, tone, and texture, making it ideal for all skin types. NAD+, on the other hand, acts at a deeper cellular level to support DNA repair, rejuvenate cells, and restore skin vitality, which is particularly beneficial for aging or stressed skin.
Application in Our Products
The Nicotinamide 10% Serum uses a high concentration of nicotinamide to target uneven skin tone, enlarged pores, and fine lines, promoting a smoother and more radiant complexion. The 9 Seconds Essence (Numbuzin No.9) is formulated with NAD+ and bio-lifting actives to rejuvenate the skin at a cellular level, enhancing elasticity and providing a visibly lifted appearance.
reference:
https://pmc.ncbi.nlm.nih.gov/articles/PMC9512238